PT-141
PT-141
PT-141 (Bremelanotide) is a brain-based approach to sexual arousal — it acts in the hypothalamus rather than on blood vessels like Viagra. FDA-approved as Vyleesi for premenopausal women.
How PT-141 Works
A deeper look for the curious
For readers who want the full mechanism — feel free to skim.
PT-141 acts in the hypothalamus of the brain — on a receptor called MC4R — to initiate sexual arousal. This is a completely different mechanism from Viagra-style drugs, which work on blood vessels. PT-141 works in the brain itself, which is why it can help people who don't respond to the blood-vessel approach.
Key Findings
What researchers have observed in studies
Acts centrally on MC4R — distinct mechanism from PDE5 inhibitors
Activates hypothalamic dopaminergic pathways
Derived from Melanotan II via metabolic modification
Melanocortin-4 receptor (MC4R)
Cyclic 7 amino acid peptide
Amino acid chain
Commonly Used For
What scientists study this compound for
Female sexual dysfunction
FDA-approved for low sexual desire in premenopausal women (as Vyleesi).
Male arousal
Researched as an alternative to PDE5 inhibitors for men who don't respond well to them.
Neurological arousal
Studied for its dopaminergic effects in the brain.
Product Features
Research Focus
HPLC Verified
High-performance liquid chromatography confirms compound purity for every batch we produce.
Mass Spec Confirmed
ESI-MS verifies molecular weight and structural identity match the target compound.
Certificate of Analysis
Complete analytical data including chromatograms and mass spectra available per batch.
Related Products
View allLaboratory use only. This product is sold for laboratory use and is not intended for human consumption or medical use.
Third-party verified. Typical purity ≥97%.