MOTS-C
MOTS-C
MOTS-c is the first peptide discovered to be produced by your mitochondria (the power plants inside your cells). It behaves like an "exercise signal in a vial" — activating the same pathway (AMPK) that a hard workout does.
How MOTS-C Works
A deeper look for the curious
For readers who want the full mechanism — feel free to skim.
MOTS-c is the first peptide discovered to be produced inside mitochondria — the energy factories of your cells. It acts like "exercise in a vial," flipping on AMPK, the same metabolic switch that a hard workout does. This improves how the body handles blood sugar and burns fat.
Key Findings
What researchers have observed in studies
First mitochondrial-encoded peptide shown to regulate nuclear genes
Activates AMPK independently of cellular energy status
Enhances glucose uptake in skeletal muscle
Exercise increases endogenous MOTS-c levels
Often Paired With
AMPK pathway / Folate-methionine cycle
16 amino acid mitochondrial-derived peptide
Amino acid chain
Commonly Used For
What scientists study this compound for
Metabolic health
Research suggests better blood sugar control, insulin sensitivity, and fat metabolism.
Mitochondrial function
Studied for rebuilding cellular energy production that declines with age.
Exercise mimetic
Produces many of the metabolic signals of exercise — appealing for recovery and aging research.
Longevity
Linked to healthier aging and extended healthspan in animal studies.
Bone health
Emerging research shows effects on osteoblast function and bone density.
Product Features
Research Focus
HPLC Verified
High-performance liquid chromatography confirms compound purity for every batch we produce.
Mass Spec Confirmed
ESI-MS verifies molecular weight and structural identity match the target compound.
Certificate of Analysis
Complete analytical data including chromatograms and mass spectra available per batch.
Related Products
View allLaboratory use only. This product is sold for laboratory use and is not intended for human consumption or medical use.
Third-party verified. Typical purity ≥97%.