KPV
KPV
KPV is a three-amino-acid fragment of the alpha-MSH hormone. Small as it is, it dampens several inflammatory signals. Research focuses on gut health and inflammatory skin conditions.
How KPV Works
A deeper look for the curious
For readers who want the full mechanism — feel free to skim.
KPV is just three amino acids — the tail end of the alpha-MSH hormone — but it keeps the anti-inflammatory punch. It blocks NF-κB, a master switch that turns on inflammation, and dials down key inflammatory signals like IL-6 and TNF-alpha.
Key Findings
What researchers have observed in studies
Inhibits NF-κB translocation to nucleus
Reduces IL-1β, IL-6, and TNF-α production
Retains anti-inflammatory activity of full alpha-MSH
Demonstrates gut barrier protective effects
Often Paired With
NF-κB pathway / Inflammasome
Tripeptide (Lys-Pro-Val)
Amino acid chain
Commonly Used For
What scientists study this compound for
Gut inflammation
Studied for IBD (Crohn's, ulcerative colitis) and leaky gut.
Skin inflammation
Investigated for eczema, psoriasis, and other inflammatory skin conditions.
Wound healing
Often combined with BPC-157 in research for broad-spectrum repair.
Product Features
Research Focus
HPLC Verified
High-performance liquid chromatography confirms compound purity for every batch we produce.
Mass Spec Confirmed
ESI-MS verifies molecular weight and structural identity match the target compound.
Certificate of Analysis
Complete analytical data including chromatograms and mass spectra available per batch.
Related Products
View allLaboratory use only. This product is sold for laboratory use and is not intended for human consumption or medical use.
Third-party verified. Typical purity ≥97%.